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Rhodamine 123 (RH-123 R-22420) is a fluorescent cationic dye used to label mitochondria in living cells Rhodamine 123 inhibits ADP-stimulated respiration of mitochondria with Ki 12 M and ATPase activity of inverted inner membrane vesicles with Ki of 126 M and partially purified F1-ATPase with Ki of 177 M
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Crocetin dialdehyde is a non-volatile apocarotenoid. It is derived from the action of the plastidic enzyme CCD2 on the carotenoid zeaxanthin, found in saffron. Crocetin dialdehyde can be converted into Crocetin (HY-N2072) by aldehyde dehydrogenases (ALDHs). Studies in mice have shown that Crocetin dialdehyde has no effect on the liver.
Non-volatile apocarotenoid.
Can be converted to Crocetin by ALDHs.
No observed effect on the liver in mice (at 300 mg/kg, p.o., for 1 week).
Purity: 99.21%.
Appearance: Solid, orange to reddish brown.
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Oxacillin-13C6 sodium is the 13C6 labeled Oxacillin sodium salt, which is a narrow-spectrum β-lactam antibiotic of the penicillin class. This compound is intended for research use only.
Used as a tracer
Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Liothyronine-13C6-1 is a 13C-labeled Liothyronine, a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively.
Can be used as a tracer
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Fostemsavir Tris (BMS-663068 (Tris)) is a phosphonooxymethyl proagent of BMS-626529. This novel attachment inhibitor targets HIV-1 gp120, preventing its binding to CD4+ T cells. It demonstrates significant antiviral activity in subjects with susceptible viruses, making it a valuable compound for research applications.
Targets HIV-1 gp120
Prevents binding to CD4+ T cells
Exhibits good antiviral activity
Intended for research use
Available as a solution in DMSO
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BSJ-03-123 is a PROTAC connected by ligands for Cereblon and CDK, functioning as a potent and novel CDK6-selective small-molecule degrader. It causes a pronounced anti-proliferative effect in CDK6-dependent AML cell lines by inducing a G1 cell-cycle arrest without a measurable increase in apoptosis.
Potent and novel CDK6-selective small-molecule degrader
Induces G1 cell-cycle arrest in AML cell lines
Causes anti-proliferative effect in CDK6-dependent AML cell lines
Does not significantly increase apoptosis
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